Article
Molecular targeted therapy in acute myeloid leukemia.
Hematology (Amsterdam, Netherlands) - 1 Apr 2012
Daver Naval, Cortes Jorge
Abstract excerpt
The treatment of acute myeloid leukemia has not changed significantly over the last 40 years. Recent progress in understanding the biology of this disease and identification of driver mutations has ushered in a new era of molecular therapeutics. Although a number of molecular markers and pathways have been identified and may serve as potential therapeutic targets, the best studied amongst these include FMS like...
Topics
- Animals
- Antineoplastic Agents
- Benzenesulfonates
- Benzothiazoles
- Humans
- Janus Kinase 2
- Leukemia, Myeloid, Acute
- Molecular Targeted Therapy
- Mutation
- Niacinamide
- Phenylurea Compounds
- Pyridines