Article
[Deletion analysis of the SUP2 gene in Saccharomyces cerevisiae].
Molekuliarnaia biologiia - 1 Jan 2000
Kushnirov V V, Ter-Avanesian M D, Dagkesamanskaia A R, Chernov Iu O, Inge-Vechtomov S G, Smirnov V N
Abstract excerpt
The sup2 mutations of the yeast Saccharomyces cerevisiae or plasmid-mediated amplification of the wild type SUP2 gene lead to suppression of different types of nonsense mutations. The Sup2 protein includes a C-terminal region homologous to elongation factor EF-1 alpha and an unique N-terminal region. The SUP2 is an essential gene. The functional role of different regions of the SUP2 gene was investigated, by...
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