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Article

Epigenetic regulation of <i>Kiss1</i> gene expression mediating estrogen-positive feedback action in the mouse brain

13 Apr 2012

Abstract excerpt

This study aims to determine the epigenetic mechanism regulating Kiss1 gene expression in the anteroventral periventricular nucleus (AVPV) to understand the mechanism underlying estrogen-positive feedback action on gonadotropin-releasing hormone/gonadotropin surge. We investigated estrogen regulation of the epigenetic status of the mouse AVPV Kiss1 gene locus in comparison with the arcuate nucleus (ARC), in which...

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PMID: 22505735
DOI: 10.1073/pnas.1114245109

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