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Article

Early Histone Modifications in the Ventromedial Hypothalamus and Preoptic Area Following Oestradiol Administration

8 Aug 2013

Abstract excerpt

Expression of the primary female sex behaviour, lordosis, in laboratory animals depends on oestrogen-induced expression of progesterone receptor (PgR) within a defined cell group in the ventrolateral portion of the ventromedial nucleus of the hypothalamus (VMH). The minimal latency from oestradiol administration to lordosis is 18 h. During that time, ligand-bound oestrogen receptors (ER), members of a nuclear...

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PMID: 23927378
DOI: 10.1111/jne.12085

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