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Article

Emerging concepts on the epigenetic and transcriptional regulation of the <i>Kiss1</i> gene

16 Mar 2013

Abstract excerpt

Kisspeptin and its receptor have been implicated as critical regulators of reproductive physiology, with humans and mice without functioning kisspeptin systems displaying severe pubertal and reproductive defects. Alterations in the expression of Kiss1 (the gene encoding kisspeptin) over development, along with differences in Kiss1 expression between the sexes in adulthood, may be critical for the maturation and...

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PMID: 23510953
DOI: 10.1016/j.ijdevneu.2013.03.006

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