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Article

Structure of Escherichia coli aspartate α-decarboxylase Asn72Ala: probing the role of Asn72 in pyruvoyl cofactor formation.

Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Apr 2012

Webb Michael E, Lobley Carina M C, Soliman Fatima, Kilkenny Mairi L, Smith Alison G, Blundell Tom L, Abell Chris

Abstract excerpt

The crystal structure of the Asn72Ala site-directed mutant of Escherichia coli aspartate α-decarboxylase (ADC) has been determined at 1.7 Å resolution. The refined structure is consistent with the presence of a hydrolysis product serine in the active site in place of the pyruvoyl group required f...

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Identifiers

PMID: 22505409
DOI: 10.1107/S1744309112009487
PMCID: PMC3325809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22505409-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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