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Article

Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver

13 Apr 2012

Abstract excerpt

UNLABELLED: Telomeres, a validated biomarker of aging, comprise multiple nucleotide repeats capping chromosomes that shorten with each cell cycle until a critical length is achieved, precipitating cell senescence. Only two previous studies focused on the effect of aging in "normal" liver tissue, but these studies were compromised by small sample size, limited age range, tissue derived from individuals with an...

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Share to Cancer Genomics and Diagnostics
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PMID: 22504828
DOI: 10.1002/hep.25787

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