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Article

Modified model of VX2 tumor overexpressing vascular endothelial growth factor.

Journal of vascular and interventional radiology : JVIR - 1 Jun 2012

Pascale Florentina, Ghegediban Saida-Homayra, Bonneau Michel, Bedouet Laurent, Namur Julien, Verret Valentin, Schwartz-Cornil Isabelle, Wassef Michel, Laurent Alexandre

Abstract excerpt

PURPOSE: To determine whether upregulated expression of vascular endothelial growth factor (VEGF) in VX2 cells can increase vessel density (VD) and reduce tumor necrosis. MATERIALS AND METHODS: The VX2 cell line was transfected with expression vectors containing cDNA for rabbit VEGF. Stable clones producing rabbit VEGF (VEGF-VX2) were selected. VEGF-VX2 cells (n = 5 rabbits) or nontransfected VX2 cells (controls;...

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Source

Identifiers

PMID: 22498170
DOI: 10.1016/j.jvir.2012.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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