Article
Th2 cell regulatory and effector molecules single nucleotide polymorphisms and periodontitis.
Journal of leukocyte biology - 1 Nov 2020
Zheng Ying, Chai Lei, Fan Yanhui, Song You-Qiang, Zee Kwan-Yat, Tu Wen Wei, Jin Lijian, Leung Wai Keung
Abstract excerpt
To investigate the association between T helper 2 (Th2) cell regulatory and effector molecules' genetic polymorphisms and periodontitis. Single nucleotide polymorphisms (SNPs) of 11 Th2 cell regulatory or effector molecules genes (CD28, CTLA4, IL4, IL5, IL6, IL9, IL10, IL13, IL4R, GATA3, STAT6, and rs1537415; total 130 SNPs) were studied in Chinese nonsmokers (163 periodontitis-free controls, 141 periodontitis...
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