Article
Expression of functional TSH receptor in white adipose tissues of hyt/hyt mice induces lipolysis in vivo.
American journal of physiology. Endocrinology and metabolism - 15 Jun 2012
Endo Toyoshi, Kobayashi Tetsuro
Abstract excerpt
To determine the relative importance of TSH in white adipose tissue, we compared the adipose phenotypes of two distinct mouse models of hypothyroidism. These models differed in that the normal reciprocal relationship between thyroid hormone and TSH was intact in one and disrupted in the other. One model, thyroidectomized (THYx) mice, had a 100-fold increase in TSH and a normal TSH receptor (TSHR); in contrast,...
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