Article
Molecular characterization of EGFR and EGFR-downstream pathways in triple negative breast carcinomas with basal like features.
Histology and histopathology - 1 Jun 2012
Martin V, Botta F, Zanellato E, Molinari F, Crippa S, Mazzucchelli L, Frattini M
Abstract excerpt
AIMS: Triple negative breast cancer with basal like features (TN-BCBL) do not benefit from hormonal and anti-HER2 therapies. As a considerable fraction of TN-BCBLs shows EGFR deregulation, EGFR-targeted therapies have been proposed as an option. The characterization of EGFR and EGFR-downstream members may therefore provide important predictive information. METHODS AND RESULTS: Based on morphological and...
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