Article
Circulating hepatitis B surface antigen particles carry hepatocellular microRNAs.
PloS one - 1 Jan 2012
Novellino Luisa, Rossi Riccardo L, Bonino Ferruccio, Cavallone Daniela, Abrignani Sergio, Pagani Massimiliano, Brunetto Maurizia R
Abstract excerpt
Hepatitis B virus (HBV) produces high quantities of subviral surface antigen particles (HBsAg) which circulate in the blood outnumbering virions of about 1\10(3-6) times. In individuals coinfected with the defective hepatitis Delta virus (HDV) the small HDV-RNA-genome and Delta antigen circulate as ribonucleoprotein complexes within HBsAg subviral particles. We addressed the question whether subviral HBsAg...
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