HOXA5 inhibits keratinocytes growth and epidermal formation in organotypic cultures in vitro and in vivo.

doi:10.1016/j.jdermsci.2012.02.019

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Article

HOXA5 inhibits keratinocytes growth and epidermal formation in organotypic cultures in vitro and in vivo.

Journal of dermatological science - 1 Jun 2012

Liang Yimin, Xia Lingling, Du Zijing, Sheng Lingling, Chen Huili, Chen Gang, Li Qingfeng

Abstract excerpt

BACKGROUND: Homeobox transcription factors play important roles in epidermal renewal. Among them HOXA5 emerges as a promising member. However, its direct effect on epidermal biology, either to promote or to inhibit growth, is still controversial. OBJECTIVE: We proposed to unravel the role of HOXA5 in modulating keratinocytes growth and epidermal formation in organotypic cultures both in vitro and in vivo....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22464764
DOI: 10.1016/j.jdermsci.2012.02.019

Genes

HOXA5
PCNA
OTC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.