Article
IGHV3-21 gene frequency in a Swedish cohort of patients with newly diagnosed chronic lymphocytic leukemia.
Clinical lymphoma, myeloma & leukemia - 1 Jun 2012
Cahill Nicola, Sutton Lesley-Ann, Jansson Mattias, Murray Fiona, Mansouri Larry, Gunnarsson Rebeqa, Ryan Fergus, Smedby Karin E, Geisler Christian, Juliusson Gunnar, Rosenquist Richard
Abstract excerpt
UNLABELLED: The IGHV3-21 gene has been shown to be overrepresented in Scandinavian patients with chronic lymphocytic leukemia (CLL). By investigating a population-based cohort of 337 Swedish patients with CLL, a lower (6.5%)IGHV3-21 frequency was determined relative to our previous hospital-based studies (10.1%-12.7%), yet this frequency remained higher compared to other Western CLL cohorts (2.6%-4.1%)....
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