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Article

Epigenetic inactivation of the E-cadherin gene in eyelid sebaceous gland carcinoma.

The British journal of dermatology - 1 Sept 2012

Jayaraj P, Sen S, Sharma A, Chosdol K, Kashyap S, Rai A, Pushker N, Bajaj M S, Ghose S

Abstract excerpt

BACKGROUND: E-cadherin and β-catenin are crucial components of the cell-cell adhesion complex. Their loss has often been associated with tumour metastasis and poor clinical outcome. Both loss of E-cadherin at the cell membrane and a stabilizing mutation in CTNNB1 (β-catenin gene) have been associ...

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Share to beta Catenin
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Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Silencing

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 22458737
DOI: 10.1111/j.1365-2133.2012.10968.x

Genes

CTNNB1
CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22458737-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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