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Article

Emerging evidence of epithelial‐to‐mesenchymal transition in lung carcinogenesis

28 Mar 2012

Abstract excerpt

The epithelial-to-mesenchymal transition (EMT) is a developmental programme that regulates embryonic morphogenesis and involves significant morphological and molecular changes in cells. Experimental models have revealed that EMT also contributes to various malignant features of cancer cells, including motile, invasive, anti-apoptotic and stem-like phenotypes. Clinically, correlative studies have indicated that...

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PMID: 22452538
DOI: 10.1111/j.1440-1843.2012.02173.x

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