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Article

Depletion of SLC4A11 causes cell death by apoptosis in an immortalized human corneal endothelial cell line.

Investigative ophthalmology & visual science - 5 Jun 2012

Liu Jun, Seet Li-Fong, Koh Li Wei, Venkatraman Anandalakshmi, Venkataraman Divya, Mohan Rajiv R, Praetorius Jeppe, Bonanno Joseph A, Aung Tin, Vithana Eranga N

Abstract excerpt

PURPOSE: To investigate the effects of SLC4A11 gene depletion in human corneal endothelial cells. METHODS: To achieve stable downregulation of SLC4A11 gene expression in immortalized human corneal endothelial cells (HCECs), short-hairpin RNA (shRNA) targeted against SLC4A11 was used. Cell growth...

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Identifiers

PMID: 22447871
DOI: 10.1167/iovs.11-8724
PMCID: PMC4007482

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22447871-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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