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Article

Inflammatory spleen monocytes can upregulate CD11c expression without converting into dendritic cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2012

Drutman Scott B, Kendall Julia C, Trombetta E Sergio

Abstract excerpt

Monocytes can differentiate into various cell types with unique specializations depending on their environment. Under certain inflammatory conditions, monocytes upregulate expression of the dendritic cell marker CD11c together with MHC and costimulatory molecules. These phenotypic changes indicat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22442444
DOI: 10.4049/jimmunol.1102741
PMCID: PMC4594880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22442444-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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