Article
Salvage treatment with lopinavir/ritonavir (Kaletra) in HIV-infected patients failing all current antiretroviral drug families.
HIV clinical trials - 1 Jan 2000
de Mendoza Carmen, Martín-Carbonero Luz, Barreiro Pablo, Diaz Beatriz, Valencia Eulalia, Jiménez-Nácher Inmaculada, Gallego Oscar, Núñez Marina, González-Lahoz Juan, Soriano Vincent
Abstract excerpt
BACKGROUND: Lopinavir/ritonavir (Kaletra) is the latest available protease inhibitor (PI). It has shown greater potency than the former PIs in phase II/III trials, either in naive or in PI-experienced patients being naive for nonnucleoside reverse transcriptase inhibitors (NNRTIs). METHOD: We analyzed the first 138 patients recruited during the expanded access program in an HIV/AIDS reference center. Only...
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