Article
Association analysis of TGFBR3 gene with Vogt-Koyanagi-Harada disease and Behcet's disease in the Chinese Han population.
Current eye research - 1 Apr 2012
Chen Yuanyuan, Yang Peizeng, Li Fuzhen, Hou Shengping, Jiang Zhengxuan, Shu Qinmeng, Kijlstra Aize
Abstract excerpt
OBJECTIVES: Transforming growth factor-β (TGF-β) has important regulating roles in the immune system, especially in the differentiation of the type 17 helper T cells (Th17 cells). In this study, we analysed the potential association of the type III TGF-β receptor (TGFBR3) genetic variations (rs2489188 and rs1805110) in the Chinese Han population for patients with either Vogt-Koyanagi-Harada (VKH) disease or...
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