Article
Characterization of OxyR as a negative transcriptional regulator that represses catalase production in Corynebacterium diphtheriae.
PloS one - 1 Jan 2012
Kim Ju-Sim, Holmes Randall K
Abstract excerpt
Corynebacterium diphtheriae and Corynebacterium glutamicum each have one gene (cat) encoding catalase. In-frame Δcat mutants of C. diphtheriae and C. glutamicum were hyper-sensitive to growth inhibition and killing by H(2)O(2). In C. diphtheriae C7(β), both catalase activity and cat transcription decreased ~2-fold during transition from exponential growth to early stationary phase. Prototypic OxyR in Escherichia...
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