Article
The nucleoside diphosphate kinase gene Nme3 acts as quantitative trait locus promoting non-Mendelian inheritance.
PLoS genetics - 1 Jan 2012
Bauer Hermann, Schindler Sabrina, Charron Yves, Willert Jürgen, Kusecek Barica, Herrmann Bernhard G
Abstract excerpt
The t-haplotype, a variant form of the t-complex region on mouse chromosome 17, acts as selfish genetic element and is transmitted at high frequencies (> 95%) from heterozygous (t/+) males to their offspring. This phenotype is termed transmission ratio distortion (TRD) and is caused by the interaction of the t-complex responder (Tcr) with several quantitative trait loci (QTL), the t-complex distorters (Tcd1 to...
Topics
- Amino Acid Sequence
- Animals
- Heredity
- Male
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Mutation
- NM23 Nucleoside Diphosphate Kinases
- Phenotype
- Protein Kinases
- Quantitative Trait Loci
- Sperm Motility
- Spermatozoa