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Article

The nucleoside diphosphate kinase gene Nme3 acts as quantitative trait locus promoting non-Mendelian inheritance.

PLoS genetics - 1 Jan 2012

Bauer Hermann, Schindler Sabrina, Charron Yves, Willert Jürgen, Kusecek Barica, Herrmann Bernhard G

Abstract excerpt

The t-haplotype, a variant form of the t-complex region on mouse chromosome 17, acts as selfish genetic element and is transmitted at high frequencies (> 95%) from heterozygous (t/+) males to their offspring. This phenotype is termed transmission ratio distortion (TRD) and is caused by the interaction of the t-complex responder (Tcr) with several quantitative trait loci (QTL), the t-complex distorters (Tcd1 to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22438820
DOI: 10.1371/journal.pgen.1002567
PMCID: PMC3305403

Genes

RHO
TRD
NME3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The nucleoside diphosphate kinase gene Nme3 acts as quantitative trait locus promoting non-Mendelian inheritance.PMID 22438820Read ↗

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Segregation distortion of mouse t haplotypes the molecular basis emerges.Semantic proximity Read ↗

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