Article
The enigma of genetics etiology of atherosclerosis in the post-GWAS era.
Current atherosclerosis reports - 1 Aug 2012
Marian A J
Abstract excerpt
Coronary atherosclerosis is a complex heritable trait with an enigmatic genetic etiology. Genome-wide association studies (GWAS) have successfully led to identification of over 100 different loci for susceptibility to coronary atherosclerosis. Most identified single nucleotide polymorphisms (SNP)s and genes have not been previously implicated in the pathogenesis of atherosclerosis and hence, have modest...
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