Article
The effect of the OPRM1 and DRD4 polymorphisms on the relation between attentional bias and alcohol use in adolescence and young adulthood.
Developmental cognitive neuroscience - 1 Oct 2011
Pieters Sara, Van Der Vorst Haske, Burk William J, Schoenmakers Tim M, Van Den Wildenberg Esther, Smeets Hubert J, Lambrichs Ellen, Field Matt, Engels Rutger C M E, Wiers Reinout W
Abstract excerpt
BACKGROUND: The incentive sensitization theory posits that in the transition from sporadic to problematic alcohol use, the incentive value of alcohol increases (wanting) while its hedonic effects (liking) do not change or decreases. The effect of the OPRM1 c.118A>G polymorphism, associated with liking and wanting, and the DRD4-VNTR polymorphism, related to wanting, on the relation between attentional bias and...
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