Article
Distribution of three SNPs related to low bone mineral density in Amerindian groups and Mestizos from Mexico.
American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000
Nuño-Arana Ismael, Sahagún-Núñez Valeria Del Rocío, Muñoz-Valle José Francisco, Sandoval Lucila, Pinto-Escalante Doris, Páez-Riberos Luis Antonio, Lazalde Brissia, Maldonado-González Montserrat, Rangel-Villalobos Héctor
Abstract excerpt
OBJECTIVES: Some Single nucleotide polymorphisms (SNPs) of several candidate genes have been associated with low bone mineral density (BMD) and fracture risk. As the genetic variability of such SNPs in Hispanic and Native American populations is scarce, we analyzed the three SNPs that have been related with bone mass disorders (Sp1, A163G, and BsmI) located in the genes of Type I Collagen (COL1A1),...
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