Article
Expression of human bone-related proteins in the hematopoietic microenvironment.
The Journal of clinical investigation - 1 Nov 1990
Long M W, Williams J L, Mann K G
Abstract excerpt
Given the intimate relationship between bone and bone marrow, we hypothesized that the human bone marrow may function as a source (or reservoir) of bone-forming progenitor cells. We observed a population of cells within the bone marrow which produce bone-specific or bone-related proteins. The production of these proteins was developmentally regulated in human long-term bone marrow cell cultures; the bone...
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