Article
Revisiting the Importance of Virulence DeterminantmagAand Its Surrounding Genes inKlebsiella pneumoniaeCausing Pyogenic Liver Abscesses: Exact Role in Serotype K1 Capsule Formation
28 Sept 2009
Abstract excerpt
BACKGROUND: Mucoviscosity-associated gene A (magA) is proposed to play a decisive role in the pathogenesis of liver abscesses due to Klebsiella pneumoniae. Although some investigators consider MagA to be a putative O-antigen ligase, it is also reportedly associated with the K1 antigen. METHODS: Using magA-positive serotype K1 K. pneumoniae STL43 isolated from a patient with liver abscess, we constructed 3...