Article
Replication analysis for severe diabetic retinopathy.
Investigative ophthalmology & visual science - 30 Apr 2012
Grassi Michael A, Tikhomirov Anna, Ramalingam Sudha, Lee Kristine E, Hosseini S M, Klein Barbara E K, Klein Ronald, Lussier Yves A, Cox Nancy J, Nicolae Dan L
Abstract excerpt
PURPOSE: The purpose of this study is to attempt to replicate the top single nucleotide polymorphism (SNP) associations from a previous genome-wide association study (GWAS) for the sight-threatening complications of diabetic retinopathy in an independent cohort of diabetic subjects from the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR). METHODS: This study included 469 type 1 diabetic, Caucasian...
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