Article
Cystic fibrosis transmembrane conductance regulator channel dysfunction in non-cystic fibrosis bronchiectasis.
American journal of respiratory and critical care medicine - 15 May 2010
Bienvenu Thierry, Sermet-Gaudelus Isabelle, Burgel Pierre-Regis, Hubert Dominique, Crestani Bruno, Bassinet Laurence, Dusser Daniel, Fajac Isabelle
Abstract excerpt
RATIONALE: Although in patients with diffuse bronchiectasis (DB) and a normal sweat test the presence of one mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene is frequently observed, its pathogenic role in the development of DB remains unclear. OBJECTIVES: To evaluat...
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