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Article

Fhos encodes a Drosophila Formin-like protein participating in autophagic programmed cell death.

Genesis (New York, N.Y. : 2000) - 1 Sept 2012

Anhezini Lucas, Saita Ana Paula, Costa Mara S A, Ramos Ricardo Guelerman Pinheiro, Simon Claudio Roberto

Abstract excerpt

Larval tissues undergo programmed cell death (PCD) during Drosophila metamorphosis. PCD is triggered in a stage and tissue-specific fashion in response to ecdysone pulses. The understanding of how ecdysone induces the stage and tissue-specificity of cell death remains obscure. Several steroid-regulated primary response genes have been shown to act as key regulators of cellular responses to ecdysone by inducing a...

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PMID: 22422652
DOI: 10.1002/dvg.22025

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