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Article

Structured three-dimensional co-culture of mesenchymal stem cells with meniscus cells promotes meniscal phenotype without hypertrophy.

Biotechnology and bioengineering - 1 Sept 2012

Cui Xiaofeng, Hasegawa Akihiko, Lotz Martin, D'Lima Darryl

Abstract excerpt

Menisci play a crucial role in weight distribution, load bearing, shock absorption, lubrication, and nutrition of articular cartilage within the knee joint. Damage to the meniscus typically does not heal spontaneously due to its partial avascular nature. Partial or complete meniscectomy is a common clinical treatment of the defective meniscus. However, this procedure ultimately leads to osteoarthritis due to...

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Source

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Identifiers

PMID: 22422555
DOI: 10.1002/bit.24495
PMCID: PMC3391334

Genes

MSC
MMP13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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