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Article

Phenotypic characterization of osteoarthritic osteocytes from the sclerotic zones: a possible pathological role in subchondral bone sclerosis.

International journal of biological sciences - 1 Jan 2012

Jaiprakash Anjali, Prasadam Indira, Feng Jian Q, Liu Ying, Crawford Ross, Xiao Yin

Abstract excerpt

Subchondral bone sclerosis is a well-recognised manifestation of osteoarthritis (OA). The osteocyte cell network is now considered to be central to the regulation of bone homeostasis; however, it is not known whether the integrity of the osteocyte cell network is altered in OA patients. The aim of this study was to investigate OA osteocyte phenotypic changes and its potential role in OA subchondral bone...

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Identifiers

PMID: 22419886
DOI: 10.7150/ijbs.4221
PMCID: PMC3303142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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