Article
Pathways and gene expression profiles in hepatocellular carcinoma.
Minerva gastroenterologica e dietologica - 1 Mar 2012
Facciorusso A, Nacchiero M C, Rosania R, Laonigro G, Giorgio F, Del Prete V, Panella C, Ierardi E
Abstract excerpt
Hepatocarcinogenesis is a process attributed to progressive genomic changes which alter the hepatocellular phenotype producing cellular intermediates evolving into clearly neoplastic cells (hepatocellular carcinoma, HCC). During the preneoplastic phase, the liver is often the site of chronic hepatitis and/or cirrhosis, and this process leads to the production of monoclonal populations of aberrant and dysplastic...
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