Article
Protein kinase A-dependent substance P expression by pituitary adenylate cyclase-activating polypeptide in rat sensory neuronal cell line ND7/23 cells.
Journal of molecular neuroscience : MN - 1 Nov 2012
Inoue Atsuko, Ohnishi Masatoshi, Fukutomi Chiharu, Kanoh Miho, Miyauchi Mutsumi, Takata Takashi, Tsuchiya Daiju, Nishio Hiroaki
Abstract excerpt
The neurotrophic effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on rat sensory neuronal cell line ND7/23 cells were investigated. PACAP caused a concentration-dependent increase in the number of neurite-bearing cells and the expression of the substance P precursor (PPT) mRNA in 24 h. The effects of PACAP were mimicked by vasoactive intestinal polypeptide with lower potency and...
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