Article
Growing pains: twin family study evidence for genetic susceptibility and a genetic relationship with restless legs syndrome.
European journal of pain (London, England) - 1 Oct 2012
Champion D, Pathirana S, Flynn C, Taylor A, Hopper J L, Berkovic S F, Jaaniste T, Qiu W
Abstract excerpt
BACKGROUND: Growing pains (GP) is a prevalent familial childhood disorder of unknown aetiology. Familial occurrence of GP, and individual and familial association of GP with restless legs syndrome (RLS) has been reported. METHODS: We applied a twin family design to search for evidence of genetic susceptibility to GP, and for a genetic relationship between GP and RLS. The parents of 1843 twin pairs aged 3-16 years...
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