Article
Association of ghrelin receptor promoter polymorphisms with weight loss following Roux-en-Y gastric bypass surgery.
Obesity surgery - 1 May 2012
Matzko Michelle E, Argyropoulos George, Wood G Craig, Chu Xin, McCarter Roger J M, Still Christopher D, Gerhard Glenn S
Abstract excerpt
BACKGROUND: Ghrelin plays a role in appetite and has been hypothesized to play a role in the mechanism of Roux-en-Y gastric bypass (RYGB) surgery. Single nucleotide polymorphisms (SNPs) in the promoter region of its receptor gene (growth hormone secretagogue receptor type 1a--GHSR) have also been associated with weight loss outcomes following long-term dietary intervention in adults with impaired glucose...
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