Identification of core genes and pathways in melanoma metastasis via bioinformatics analysis

Abstract excerpt

<title>Abstract</title> <p>Background Metastasis is the leading cause of melanoma mortality. Current therapies are rarely curative for metastatic melanoma, revealing the urgent need to identify more effective preventive and therapeutic targets. This study aimed to screen for the key core genes and molecular mechanisms related to the metastasis of melanoma. Methods Gene expression profile, GSE8401 including 31...

Topics

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• Cancer Immunotherapy and Biomarkers
• Cutaneous Melanoma Detection and Management
• Cytokine Signaling Pathways and Interactions
• Ferroptosis and cancer prognosis
• FOXO transcription factor regulation
• Melanoma and MAPK Pathways
• Skin and Cellular Biology Research
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

fbb94cdb-1792-5495-8e47-21fbd6aa8516

DOI

10.21203/rs.3.rs-39969/v1