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Article

Association of X-ray repair cross-complementing group 1 promoter rs3213245 polymorphism with lung cancer risk.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014

Wang Ruotian, Zhang Yi, Zhang Jian, Zhi Xiuyi

Abstract excerpt

X-ray repair cross-complementing group 1 (XRCC1) is a major DNA repair protein in the base excision repair pathway. XRCC1 rs3213245 is a functional polymorphism in the XRCC1 gene promoter region which results in decreased DNA repair capacity. Previous studies investigating the association of XRCC1 rs3213245 polymorphism with lung cancer risk reported conflicting results. A meta-analysis of published studies was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins
Share to Genetic Association Studies
Share to Lung Neoplasms
Share to Odds Ratio
Share to Polymorphism, Single Nucleotide
Share to Promoter Regions, Genetic
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Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 24470137
DOI: 10.1007/s13277-013-1435-2

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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