Article
Maternal imprinting and female predominance in familial Crohn's disease.
Journal of Crohn's & colitis - 1 Aug 2012
Zelinkova Zuzana, Stokkers Pieter C, van der Linde Klaas, Kuipers Ernst J, Peppelenbosch Maikel P, van der Woude Christine P J
Abstract excerpt
BACKGROUND AND AIM: Although the genetic risk factors for familial and sporadic inflammatory bowel disease (IBD) seem identical, the relative risk for contracting IBD in the familial setting is larger as that seen in the population at large, suggesting an important role of epi- and/or paragenetic factors in familial IBD. Epidemiological data indicate a female predominance in IBD, but how this relates to familial...
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