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Smoking and inflammatory bowel disease: trends in familial and sporadic cohorts.

Inflammatory bowel diseases - 1 May 2007

Tuvlin Jeffrey A, Raza Sania S, Bracamonte Samuel, Julian Christina, Hanauer Stephen B, Nicolae Dan L, King Andrea C, Cho Judy H

Abstract excerpt

BACKGROUND: Ulcerative colitis (UC) and Crohn's disease (CD) result from genetic and environmental factors. Never smoking and formerly smoking increase the risk of UC, whereas smoking exacerbates the course of CD. We sought to define the age-dependent effects of smoking on the development of UC and CD in familial and sporadic cohorts. METHODS: University of Chicago patients diagnosed with UC or CD between 1990...

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PMID: 17345609
DOI: 10.1002/ibd.20043

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