Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The high‐mobility group A1‐estrogen receptor β nuclear interaction is impaired in human testicular seminomas

6 Mar 2012

Abstract excerpt

It is well established that estrogens participate in the control of normal spermatogenesis and endogenous or environmental estrogens are involved in pathological germ cell proliferation including testicular germ cell tumors. The effects of estrogen are now known to be mediated by estrogen receptor-α (ERα) and ERβ subtypes, but only ERβ has been found in human germ cells of normal testis. However, its expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sperm and Testicular Function
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22392906
DOI: 10.1002/jcp.24087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The high‐mobility group A1‐estrogen receptor β nuclear interaction is impaired in human testicular seminomasPMID 22392906Read ↗

High Levels of Gpr30 Protein in Human Testicular Carcinoma In Situ and Seminomas Correlate with Low Levels of Estrogen Receptor‐Beta and Indicate a Switch in Estrogen ResponsivenessSemantic proximity Read ↗

Estrogen Receptors α and β in Human Testis: Both Isoforms are ExpressedSemantic proximity Read ↗

HMGA1-Regulating microRNAs Let-7a and miR-26a are Downregulated in Human SeminomasSemantic proximity Read ↗

Down‐regulation of oestrogen receptor‐β associates with transcriptional co‐regulator PATZ1 delocalization in human testicular seminomasSemantic proximity Read ↗

Estrogens in Testis BiologySemantic proximity Read ↗

Estradiol Signaling at the Heart of Folliculogenesis: Its Potential Deregulation in Human Ovarian PathologiesSemantic proximity Read ↗

GPR30, the Non-Classical Membrane G Protein Related Estrogen Receptor, Is Overexpressed in Human Seminoma and Promotes Seminoma Cell ProliferationSemantic proximity Read ↗

Estrogen receptor beta (ERβ) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter geneSemantic proximity Read ↗

Differential distribution of splice variants of estrogen receptor beta in human testicular cells suggests specific functions in spermatogenesisSemantic proximity Read ↗

Towards understanding biology of leydiogioma. G protein-coupled receptor and peroxisome proliferator-activated receptor crosstalk regulates lipid metabolism and steroidogenesis in Leydig cell tumorsSemantic proximity Read ↗

Estrogen receptor-α is required by the supporting somatic cells for spermatogenesisSemantic proximity Read ↗

Estrogen signaling, through estrogen receptor β, regulates DNA methylation and its machinery in male germ line in adult ratsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.