Article
The absence of polymorphisms in ADRB3, UCP1, PPARγ, and ADIPOQ genes protects morbid obese patients toward insulin resistance.
Journal of endocrinological investigation - 1 Jan 2012
Bracale R, Labruna G, Finelli C, Daniele A, Sacchetti L, Oriani G, Contaldo F, Pasanisi F
Abstract excerpt
BACKGROUND AND AIMS: The insulin resistance (IR) is a major metabolic impairment in severe obesity, a multifactorial disease in which the importance of the effect of single nucleotide polymorphisms (SNP) associations in different rather than individual genes was established. The aim of this study was to test the predictive value of presence/absence of polymorphisms/ variants in β3-adrenergic receptor (ADRB3),...
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