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Article

High on-treatment platelet reactivity by ADP and increased risk of MACE in good clopidogrel metabolizers.

Platelets - 1 Jan 2012

Marcucci Rossella, Giusti Betti, Paniccia Rita, Gori Anna Maria, Saracini Claudia, Valente Serafina, Giglioli Cristina, Parodi Guido, Antoniucci David, Gensini Gian Franco, Abbate Rosanna

Abstract excerpt

High on-treatment platelet reactivity (HPR) by ADP, which primarily reflects the effect of thienopyridines, has been found to be an independent predictor of ischemic events in patients with acute coronary syndrome (ACS) on dual antiplatelet therapy. CYP2C19*2 is associated with HPR by ADP. The aim of our study was to evaluate if high on-clopidogrel platelet reactivity (HPR) by ADP is associated with an increased...

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Identifiers

PMID: 22390861
DOI: 10.3109/09537104.2012.658106

Genes

HPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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