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Article

Familiality of temperament in bipolar disorder: support for a genetic spectrum.

Journal of affective disorders - 1 Mar 2005

Evans Lynn, Akiskal Hagop S, Keck Paul E, McElroy Susan L, Sadovnick A Dessa, Remick Ronald A, Kelsoe John R

Abstract excerpt

BACKGROUND: The array of different diagnoses and clinical presentations seen in the family members of bipolar probands suggests a quantitative or spectrum phenotype. Consistent with this idea, it has been proposed that an underlying quantitative variation in temperament may be the primary phenotype that is genetically transmitted and that it in turn predisposes to bipolar disorder (BP). Choosing the appropriate...

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Identifiers

PMID: 15780686
DOI: 10.1016/j.jad.2003.10.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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