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Article

Association of MBL2 gene exon 1 variants with autoimmune thyroid disease in Brazilian patients.

International journal of immunogenetics - 1 Aug 2012

Filho C B, Rodrigues F F, Segat L, Fonseca A M, Araujo J, Arahata C, Pontes L, Vilar L, de Lima Filho J L, Crovella S

Abstract excerpt

We investigated the association between MBL2 gene exon 1 functional polymorphisms and autoimmune thyroid disease (AITD) in 163 Brazilian patients (87 with Hashimoto thyroiditis, HT; 76 with Graves' disease) and 214 healthy controls. Individuals carrying MBL2 O allele are at higher risk of developing AITD (OR = 1.58, 95% CI: 1.11-2.26; P-value = 0.009) and HT (OR = 1.67, 95% CI: 1.09-2.55; P-value = 0.013) as...

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Identifiers

PMID: 22360648
DOI: 10.1111/j.1744-313X.2012.01102.x

Genes

MBL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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