Binding of ubiquitin conjugates to proteasomes as visualized with native gels.

Abstract excerpt

The proteasome is an ATP-dependent molecular machine that degrades proteins through the concerted activity of dozens of subunits. It is the yin to the ribosome's yang, and together these entities mold the protein landscape of the cell. Native gels are generally superior to conventional and affinity purifications for the analytical resolution proteasomal variants, and have thus become a staple of proteasome work....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Proteasome Endopeptidase Complex
• Share to Proteolysis
• Share to Electrophoresis, Polyacrylamide Gel