Chemical proteomics profiling of proteasome activity.

doi:10.1385/1-59745-026-X:51

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Chemical proteomics profiling of proteasome activity.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006

Verdoes Martijn, Berkers Celia R, Florea Bogdan I, van Swieten Paul F, Overkleeft Herman S, Ovaa Huib

Abstract excerpt

Proteolysis is a key mechanism for protein homeostasis in living cells. This process is effected by different classes of proteases. The proteasome is one of the most abundant and versatile proteases, bearing three different proteolytic active sites. The proteasome plays an important role in essential biological pathways such as antigen presentation, signal transduction, and cell-cycle control feedback loops. The...

Topics

Blotting, Western
Catalysis
Cell Line
Electrophoresis, Gel, Two-Dimensional
HeLa Cells
Humans
Models, Biological
Models, Chemical
Oligonucleotide Probes
Peptide Hydrolases
Phenotype
Proteasome Endopeptidase Complex
Proteomics
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 16785641
DOI: 10.1385/1-59745-026-X:51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics