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Article

Chemical proteomics profiling of proteasome activity.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006

Verdoes Martijn, Berkers Celia R, Florea Bogdan I, van Swieten Paul F, Overkleeft Herman S, Ovaa Huib

Abstract excerpt

Proteolysis is a key mechanism for protein homeostasis in living cells. This process is effected by different classes of proteases. The proteasome is one of the most abundant and versatile proteases, bearing three different proteolytic active sites. The proteasome plays an important role in essential biological pathways such as antigen presentation, signal transduction, and cell-cycle control feedback loops. The...

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PMID: 16785641
DOI: 10.1385/1-59745-026-X:51

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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