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Article

Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation.

Human molecular genetics - 1 Jun 2012

Woods Rima, Vallero Roxanne O, Golub Mari S, Suarez Joanne K, Ta Tram Anh, Yasui Dag H, Chi Lai-Har, Kostyniak Paul J, Pessah Isaac N, Berman Robert F, LaSalle Janine M

Abstract excerpt

The widespread use of persistent organic polybrominated diphenyl ethers (PBDEs) as commercial flame retardants has raised concern about potential long-lived effects on human health. Epigenetic mechanisms, such as DNA methylation, are responsive to environmental influences and have long-lasting consequences. Autism spectrum disorders (ASDs) have complex neurodevelopmental origins whereby both genetic and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22343140
DOI: 10.1093/hmg/dds046
PMCID: PMC3349420

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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