Article
Quantification of Plasmodium falciparum malaria from complex infections in the Peruvian Amazon using quantitative PCR of the merozoite surface protein 1, block 2 (PfMSP1-B2): in vitro dynamics reveal density-dependent interactions.
Parasitology - 1 May 2012
Zervos Thomas M, Hernandez Jean N, Sutton Patrick L, Branch Oralee H
Abstract excerpt
The majority of Plasmodium falciparum field isolates are defined as complex infections because they contain multiple genetically distinct clones. Studying interactions between clones in complex infections in vivo and in vitro could elucidate important phenomena in malaria infection, transmission and treatment. Using quantitative PCR (qPCR) of the P. falciparum merozoite surface protein 1, block 2 (PfMSP1-B2), we...
Topics
- Animals
- DNA, Protozoan
- Genotype
- Humans
- Malaria, Falciparum
- Merozoite Surface Protein 1
- Peru
- Plasmodium falciparum
- Polymerase Chain Reaction
- Protozoan Proteins