Article
An instructive case suggesting warfarin resistance which is independent on the regulation of the CYP2C9 and VKORC1 genotype.
Rinsho byori. The Japanese journal of clinical pathology - 1 Dec 2011
Nishimura Fumitaka, Tokuda Masahiro, Sasaki Daisuke, Mori Sayaka, Tsuruda Kazuto, Hasegawa Hiroo, Yanagihara Katsunori, Kamihira Shimeru
Abstract excerpt
To improve the safety and effectiveness of warfarin (WF) therapy, the initial dose trends to be practically decided based on single nucleotide polymorphism (SNP) genotyping of two genes, cytochrome P450 (CYP) 2C9 and vitamin K epoxide reductase complex1 (VKORC1). We encountered a 43-year-old fema...
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